In 1999, carrier and its battle group were tasked with following a Russian Oscar-class submarine, SSGN Minsk, spotted near Macross Island to see if rumor that the Russians had sold it to a foreign power was true. A sub-hunter from the carrier was destroyed by unknown fighters and in response the carrier launched Skull Squadron to hunt down the culprits. When its aircraft were engaged by unknown fighters.
During the engagement the SDF-1 entered Earth's atmosphere and on its decent to Macross Island passed relatively close to the Kenosha's battle group, capsizing the carrier and sinking its entire battle group.
The only survivors were Admiral Hayes, who had been recalled to the Pentagon only minutes before the SDF-1 entered Earth's atmosphere, and Lieutenant Roy Fokker who was in the air and managed to gain enough altitude to avoid the blast wave of the crash. (Comic: "Robotech: From the Stars 1: From the Stars")
Behind the Scenes
While no aircraft carrier by that name has served in the US Navy, the name USS Kenosha has been used twice historically. It was first used for a wooden-hulled sloop commissioned in 1869, which was later renamed the USS Kenosha. In 1945, an Alamosa-class cargo ship was commissioned as the second USS Kenosha AK-190.
In spite of its high hull number (the USN is currently fitting out CVN-78 PCU Gerald R. Ford and building CVN-79 PCU John F. Kennedy), Kenosha's island visibly resembles that of USS Enterprise (CVN-65), commissioned in 1961. Enterprise's distinctive beehive-over-cube island was designed around a phased array radar that never worked right and an electronic warfare suite that worked just fine.
Like the historical ships of that name, the USS Kenosha is presumably named after Kenosha, Wisconsin.